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Q&A: Understanding The Latest COVID-19 Variants And Vaccines
As COVID-related hospitalizations once again increase across the U.S., experts are researching the newly identified variants, their transmissibility and possible mutations. How concerned should the public be about these new variants? What is a good time to get fall vaccines? Can we expect the reinstitution of mask and social distancing regulations?
Jodie Guest, Ph.D., professor and senior vice chair of the department of epidemiology at Emory's Rollins School of Public Health, teamed up with Carlos del Rio, MD, distinguished professor of medicine, epidemiology and global health, interim dean of Emory University School of Medicine and interim chief academic officer at Emory Health care, to answer these questions and more.
Q: To what do you attribute the recent increase in COVID-19 hospitalizations and deaths?A: Unfortunately, the vaccination coverage in the U.S. Is not ideal. If you look who has been vaccinated with the last booster, it is only about 16% of the U.S. Population and it's only about 46% of those people over the age of 65. The target should be, how we get people over the age of 65 vaccinated because those are the people we are seeing hospitalized.
Q: On Wednesday, the CDC issued its initial risk assessment for the new BA.2.86 variant, which says existing tests, treatments and updated vaccines will likely still be effective, but it "may be more capable of causing infection in people who have previously had COVID-19 or who have received COVID-19 vaccines." What does this mean?A: What is different about this variant is that it has more than 30 (mutations) than the previous variant that was circulating. This is about equivalent to what the initial omicron variant was compared to the delta variant. And if you remember, we saw a massive increase in cases with omicron.
So what people are very concerned about is what is going to happen if this variant is that different. Are we not going to have enough immunity to prevent people from getting infected? But the good news is that it appears the existing treatment and testing work, and that the updated booster, which should hopefully come out in a few weeks, does appear to have some level of immunity and should continue to have significant protection against hospitalization, severe disease and death. This again emphasizes why (being up to date on vaccines) is so important.
Credit: Emory University Q: The new vaccines are due out in September and should be widely available in October. Considering the current rise in COVID-19 cases, should people get the booster that is currently available or wait for the updated booster?A: If you have been vaccinated previously, the recommendation is to wait until this new vaccine is available. If you have not been vaccinated previously, then you could get vaccinated now and get that initial vaccine dose.
Q: Do you feel comfortable getting the seasonal flu shot and the updated COVID vaccine at the same time this year?A: Yes, and I would also feel comfortable getting the RSV vaccine. The reality is that we now have vaccines against those respiratory viruses and for people over the age of 60—who are at high risk of hospitalization and death—that would be a good thing to do. Many of us are expecting what we've seen in the past, which is an early RSV wave, followed by a flu wave and finishing off with a COVID-19 wave. So we're going to see those viruses close circulating on our community and if you're over the age of 60, you want to avoid them.
Q: Some people are calling for the return of masks. Do you suspect that we will see an increase in the use of masks or a mandate for masking?A: I don't think we're going to see mandates for masking anymore. But masking works, especially if you use the right mask. So, this is where I think people have to make their own risk assessment, especially if they are over the age 60 or have some health issues.
Citation: Q&A: Understanding the latest COVID-19 variants and vaccines (2023, August 30) retrieved 30 August 2023 from https://medicalxpress.Com/news/2023-08-qa-latest-covid-variants-vaccines.Html
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Testing, Vaccines, Lockdowns And Masks: LSU Health Doctor Explains New COVID Variant Risks
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Child Vaccines Due As Students Return To Class. Here's What You Need To Know.
By Jennifer FernandezA series of child cartoon characters dressed in superhero outfits introduce topics such as the importance of child vaccinations in a series of health department videos.
The videos feature Jennifer Mullendore, medical director for Buncombe County, where a large number of children are not fully immunized. The county has seen outbreaks in recent years of preventable diseases such as chickenpox.
"These vaccine preventable diseases still exist in our community," Mullendore said in one of the county health department's videos that encourage residents to get their children vaccinated as part of the "A Shield of Protection for Your Child's Health" campaign.
"If enough people are unvaccinated, it allows holes in that shield," Mullendore said in that video. "Diseases can get in and then cause devastation in those people who don't have the vaccine."
Although the videos were part of a vaccination campaign from several years ago, the message is still relevant.
"We have so much research that vaccines prevent diseases, and we all want kids to be healthy and thrive," said Elizabeth Hudgins, executive director of the North Carolina Pediatric Society.
As children head back to classrooms for the 2023-24 academic year, pediatricians, schools and health departments are working to get kids up to date on required vaccinations. Most public schools resume classes this week.
While North Carolina's child vaccination rates are better than the national average, it's important to keep inoculation rates above 95 percent, according to Brian Bowman, a pediatrician with Apex Pediatrics in Apex.
That 95 percent mark is the threshold that experts say is needed to keep infectious diseases at bay.
"When we drop below 95 percent in a community, then that can be a problem," he said.
North Carolina requires all children — with some exceptions — to be vaccinated before attending child care or school, whether public or private. If students don't have the required vaccinations, they won't be allowed at school.
Last year, nearly 12 percent of high school students had not been fully vaccinated within the first month of school, state data show.
Not common, but not goneIn the early to mid-20th century, childhood illnesses such as polio and the measles were common, but vaccines have all but eradicated these infectious diseases.
Zack Moore, state epidemiologist and the epidemiology section chief in the Division of Public Health of the N.C. Department of Health and Human Services, called childhood vaccinations "one of the biggest advances we've had in public health."
Yet cases and outbreaks still happen. Last year, New York state officials identified a case of polio in an unvaccinated young adult who became paralyzed. It was the first case in the country in a decade.
In 2019, the CDC confirmed 1,274 individual cases of the highly contagious measles in 31 states. It marked the greatest number of measles cases reported in the U.S. Since 1992. The majority of cases were among unvaccinated people.
"When you have pockets of people who are not protected, it can spread really quickly," Moore said.
North Carolina is not immune to outbreaks of diseases that can be prevented through vaccination. Since October 2018, there have been more than two dozen of them, officials with NCDHHS told NC Health News.
Of those outbreaks, 21 involved illnesses that children must be vaccinated against before going to child care or school.
Whooping cough accounted for 16 of the outbreaks. Also known as pertussis, whooping cough is caused by a bacterial infection that can be life-threatening, especially for infants. The name "whooping cough" comes from the "whooping" sound made when those infected infants, with tiny airways, gasp for air after a fit of coughing. In a 2012 outbreak in Winston-Salem, a 2-month-old died.
Because pertussis is caused by a bacterial infection, the protection given by a vaccine wanes over time, so it's important for elementary school-aged children to get a booster, especially if they live in a family with infants.
There were three outbreaks of varicella, more commonly known as chickenpox, and two of mumps.
Chickenpox is a highly contagious disease caused by a virus. It causes an itchy, blister-like rash and can be life-threatening in babies and adolescents. Mumps, another very contagious disease caused by a virus, is marked by swelling of the salivary glands. It can lead to inflammation, including of the brain and the tissue surrounding the brain and spinal cord. For older males who contract the disease, mumps can cause permanent problems with sperm formation, leading to infertility.
One of the chickenpox outbreaks in 2018 affected a private school in Buncombe County where most of the children were unvaccinated, said Ellis Matheson, director of Buncombe County Public Health.
Such outbreaks affect more than student health, she said.
"If you can't show immunity to the disease, you can be excluded from school until the outbreak is over, which sometimes can be for weeks," Matheson said.
A quarantine can lead to economic and education repercussions, as well, she said, as parents have to take time off work to be with their children, who lose important time being in school.
Moore said whooping cough and chickenpox outbreaks typically occur in child care settings and schools, especially those with high rates of exemption, when a person cites a medical or religious reason to not get vaccinated. Mumps outbreaks tend to be on college campuses, usually among students who've been vaccinated, Moore said.
No vaccine guarantees 100 percent protection against an illness. However, those who are vaccinated and become ill have milder symptoms, according to the Centers for Disease Control and Prevention.
ExemptionsA smaller percentage of North Carolina children are being exempted from getting vaccinated for non-medical reasons compared to children nationwide, data show. But that number is growing at a faster rate in North Carolina than the nation.
In North Carolina, non-medical exemptions rose from 0.7 percent to 1.8 percent over a decade through the 2021-22 school year, the most recent CDC data show.
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Over that same time period, non-medical exemptions nationwide rose from 1.4 percent to 2.3 percent.
"We have seen a little uptick in exemptions for the required vaccines," Moore said. "But it's still relatively low, just over 2 percent for kindergarten across the state. It's particularly gone up in kids enrolled in private schools."
Still, that uptick across the nation is a concern "and speaks for a need for continuing education," he said.
North Carolina fares better than the nation as a whole for the percentage of children receiving various vaccinations.
For example, 95.9 percent of N.C. Children have been inoculated against chickenpox, according to CDC data for the 2021-22 school year. By comparison, 92.1 percent of children nationwide have gotten the vaccine.
"The bigger issue is people who do want the vaccines but have an issue with access," Moore said, referring to such common issues as transportation, insurance and even provider availability that can prevent people from getting needed care.
Distrust, misinformationMoore said medical professionals are still seeing a lot of misinformation and disinformation on the COVID-19 vaccines, and by extension, other vaccines.
An October 2022 article, later published in The Lancet, looked at how to keep that fear over the COVID-19 vaccine from bubbling over into routine childhood vaccinations.
"It is important that we act now to ensure childhood vaccination –– a cornerstone of public health –– remains trusted, valued, and equitably accessed," the authors wrote.
Bowman said he is having more discussions with patients about vaccine safety than he was before. Being compassionate about their concerns is important, he said; otherwise, they won't trust the answers given to them.
Listening is key, as is persistence in bringing up the topic at each visit to encourage parents to continue the discussion, Matheson said.
"Because it could be that 10th visit where someone is ready to have a deeper conversation and receive more information and, ultimately, hopefully, get vaccines for themselves or their children," she said.
So far, there has been no detectable change in vaccine rates tied to COVID-19 concerns in the state, Moore said.
"Overall, parents and pediatricians are still doing a really good job of vaccinating their kids against other vaccine preventable diseases," he said.
Vaccination policyIn North Carolina, vaccination records are checked when a child is enrolled in a child care facility or school. Children are not allowed to attend school (whether public, private or religious) or a child care facility unless they have received all required immunizations appropriate for their age or been exempted.
Families have 30 days from the first day a student attends school to provide proof the child has received all required immunizations for that age. After that, the student can't attend school until the family provides documentation of vaccinations or an exemption.
The state allows for two types of exemption — medical and religious belief.
The medical exemption requires a licensed physician to fill out a form explaining why the child can't be vaccinated. An allergy to a vaccine component, for example, can qualify a child for a medical exemption.
For a religious exemption, the child's parent or guardian just needs to write a statement explaining their "bona fide religious beliefs and opposition to the immunization requirements," according to state law. The statement must include the child's name and date of birth. It does not need to be notarized or approved by any state agency.
Non-religious personal beliefs, however, are not accepted as a reason for exemption, according to state law.
Need to get vaccinated? Find a vaccination site at https://vaccinefinder.Org.
Views on required vaccinations may be changing.
Fewer parents say healthy children should get the combo MMR vaccine (mumps, measles, rubella) before attending school, according to the KFF Vaccine Monitor.
The number dropped to 71 percent in December, compared with 82 percent who said the same in an October 2019 Pew Research Center poll.
The number who say parents should be able to decide not to vaccinate their school-age children, even if it creates health risks for others, has increased from 16 percent to 28 percent.
Vaccination requirements
North Carolina law requires that children get certain vaccinations unless an exemption is requested. Here's a look at required vaccinations and when they must be taken by:
To enter child care
To enter kindergarten
Must have received the vaccinations required to attend child care. No additional vaccinations required.
To enter seventh grade
Must have received the vaccinations required to attend child care/kindergarten, plus:
To enter 12th grade
Must have received the vaccinations required to attend child care/kindergarten/seventh grade, plus:
Source: NCDHHS
Reporting complicationMeanwhile, health officials have less money to combat the drop in vaccinations.
The CDC has slashed vaccination program funding by what amounts to about 10 percent, officials told KFF Health News in early July.
CDC officials said in an email obtained by the nonprofit newsroom that the cut may result in less complete reporting on vaccinations.
However, Matheson said that the cut in federal funding won't impact the Vaccines for Children Program, which provides vaccines at no cost to children who might not otherwise be vaccinated because of inability to pay.
"People who are not insured, who need the vaccines for their children, absolutely can come into our clinic and receive those vaccines," she said. "There's also many other programs out there that help with vaccines."
The CDC officials said the loss in funding is connected to the debt limit deal struck between the Biden administration and Congress in June.
It's not the first health care issue affected by the budget deal. Lawmakers also clawed back $400 million of COVID-19 pandemic aid that had been used by the CDC to hire 3,000 disease intervention specialists — public health workers who do contact tracing, investigate disease outbreaks and connect people to testing and treatment services, including for sexually transmitted infections.
"It's not the time to be going backwards on this," Hudgins said about routine childhood vaccination funding.
Recommended, not requiredAlong with the slate of vaccinations required by state law, health officials recommend children be vaccinated for a few more illnesses before school starts.
Some of the recommended vaccines would stop the spread of a trifecta of respiratory illnesses that last fall hobbled some North Carolina hospitals that didn't have enough beds for children affected. They had to divert child patients to other facilities because so many came in with either the flu, COVID-19 or respiratory syncytial virus, also known as RSV.
RSV usually causes mild, cold-like symptoms. However, it can be more severe for older adults and for infants — and lead to hospitalization.
Health officials such as Buncombe County's Matheson are encouraging families this year to get the flu and COVID-19 vaccines, as well as RSV for those most vulnerable.
Buncombe County has a mobile clinic that can help with those vaccines, and it is adding more staff and extending hours at its main clinic to help children get their required vaccinations for school.
"We're really just encouraging everyone to assess their own vaccine status and everybody to get caught up," Matheson said, "to create that shield of protection on themselves and their family and community."
The CDC recommends the HPV vaccine be taken typically between age 11-12, or at least by age 26. The Food and Drug Administration approved an HPV vaccine in 2014.
It protects against infections from the human papillomavirus that can later cause certain types of cancer, such as cervical, penile or anal cancer. Since the initiation of HPV vaccine, the incidence of cervical cancer has decreased more rapidly, leading researchers to believe this is because of the vaccine being widely available.
HPV is the most common sexually transmitted infection, according to the CDC, with infections so common that most people will have at least one in their lifetime.
However, coverage rates in North Carolina are not as good as officials would like them to be, Moore said.
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