Combining genetics and brain MRI can aid in predicting chances of Alzheimer's disease - Science Daily
Simon Fraser University researchers are studying how a combination of genetics and brain MRIs may be used to predict the chances of developing Alzheimer's disease in the future. In a newly published study, researchers from SFU's Functional and Anatomical Imaging & Shape Analysis Lab (FAISAL) identified distinct properties of brain MRIs and genetics that impact the prediction of Dementia of Alzheimer's Type, or DAT, for patients at various stages of the disease, then developed a biomarker that can help predict future conversion to DAT. "Our findings reveal that while genetic features have lower predictive power than MRI features, combining both modalities can improve the performance in predicting the future conversion to DAT," says study lead author Ghazal Mirabnahrazam, a research assistant currently completing a master's degree in engineering science at SFU. Dementia scores based on genetic data were shown to better predict future DAT progressio...